Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 54
Filtrar
1.
Med Oral Patol Oral Cir Bucal ; 28(2): e148-e155, 2023 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-36806024

RESUMO

BACKGROUND: The significant advances in the materials and biological aspects of dental implants haven't completely eradicated the implant failures. The removal of osseointegrated but otherwise failed implants present several challenges including adjacent tissues damage and necessity of bone augmentation for reimplantation. Controlled thermal necrosis has emerged as an alternative technique to aid removal of osseointegrated dental implants with minimal to no defect to healthy bone or surrounding tissues. This study aimed to evaluate the thermal necrosis-aided implant removal method in a rabbit osseointegration model. MATERIAL AND METHODS: A total of 8 male New Zealand rabbits were used in the study. Two dental implants were placed on each femur of the rabbits. Heating of the implants was performed after 7 weeks following the implantation. Heating was done by contacting the tip of an electrosurgey tool in monopolar mode at different power settings and contact durations (5W - 2 seconds, 5W - 10 seconds, and 10 W - 10 seconds). No heating was done on the control group. Implant stability right after implantation, before heat application and after heat application was determined using an Osstell™ Mentor Device. Following the removal of implants histological analyses were performed to determine the effects of heat application at cellular level. RESULTS: ISQ values of the 10W-10s group was significantly lower compared to the other groups (p<0.001). No indication of progressive necrosis or irreversible damage was observed in any of the groups. However, the percent of empty-apoptotic lacunae were statistically higher in the 5W-10s and the 10W-10s groups compared the control and the 5W-2s groups. CONCLUSIONS: Within the conditions of this study, we conclude that heat application with an electrosurgery tool using monopolar mode at 10W power for 10 seconds is optimal for reversing osseointegration with no extensive or progressive damage to the bone.


Assuntos
Implantes Dentários , Coelhos , Masculino , Animais , Projetos Piloto , Implantação Dentária Endóssea/métodos , Osseointegração , Eletrocirurgia , Titânio/farmacologia , Propriedades de Superfície
2.
Curr Med Imaging ; 17(3): 352-365, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-32748753

RESUMO

BACKGROUND: Cluster analysis is a robust tool for exploring the underlining structures in data and grouping them with similar objects. In the researches of Functional Magnetic Resonance Imaging (fMRI), clustering approaches attempt to classify voxels depending on their time-course signals into a similar hemodynamic response over time. OBJECTIVE: In this work, a novel unsupervised learning approach is proposed that relies on using Enhanced Neural Gas (ENG) algorithm in fMRI data for comparison with Neural Gas (NG) method, which has yet to be utilized for that aim. The ENG algorithm depends on the network structure of the NG and concentrates on an efficacious prototype-based clustering approach. METHODS: The comparison outcomes on real auditory fMRI data show that ENG outperforms the NG and statistical parametric mapping (SPM) methods due to its insensitivity to the ordering of input data sequence, various initializations for selecting a set of neurons, and the existence of extreme values (outliers). The findings also prove its capability to discover the exact and real values of a cluster number effectively. RESULTS: Four validation indices are applied to evaluate the performance of the proposed ENG method with fMRI and compare it with a clustering approach (NG algorithm) and model-based data analysis (SPM). These validation indices include the Jaccard Coefficient (JC), Receiver Operating Characteristic (ROC), Minimum Description Length (MDL) value, and Minimum Square Error (MSE). CONCLUSION: The ENG technique can tackle all shortcomings of NG application with fMRI data, identify the active area of the human brain effectively, and determine the locations of the cluster center based on the MDL value during the process of network learning.


Assuntos
Mapeamento Encefálico , Imageamento por Ressonância Magnética , Encéfalo/diagnóstico por imagem , Análise por Conglomerados , Análise de Dados , Humanos
3.
Folia Morphol (Warsz) ; 78(1): 153-162, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30009362

RESUMO

BACKGROUND: Nasopalatine canal (NPC) (incisive canal) morphology is important for oral surgery techniques carried out on the maxilla, in the treatment of naso- palatine cyst, palatal pathologies that require a surgical intervention. MATERIALS AND METHODS: The morphology of NPC was classified in sagittal, coronal and axial planes on the cone beam computed tomography (CBCT). The length of NPC was found by measuring the distance between the mid-points of nasopalatine foramen and incisive foramen. The numbers, shapes and diameters of incisive and nasopalatine foramina were examined. Nasopalatine angle present between the NPC and the palate and anterior to the NPC was measured. RESULTS: In the sagittal plane, the shape of NPC was classified in six groups: 26.7% hourglass, 14.7% cone, 13.3% funnel, 16.0% banana, 28.7% cylindrical and 0.7% reverse-cone-shaped. In the coronal plane, shape of NPC was classified in three groups: 63.3% Y-shaped, 36.0% single canal, 0.7% double canal and external border of NPC was classified in four groups: 26.7% U, 28.7% Y, 44.0% V and 0.7% reverse-V-shaped. In the axial plane, the shape of nasopalatine foramen, incisive foramen and NPC at the mid-level was evaluated. The shape of the canal was detected as four types at three evaluated levels: round, oval, heart- and triangle-shaped. It was seen in every three axial planes that the round group is more than the others. CONCLUSIONS: The morphological properties and variations of NPC should be con- sidered with a correct radiological evaluation so as to prevent the complications and improper practices in local anaesthesia, maxillary surgery and implant surgery practices. Especially dentists, otolaryngologist and plastic surgeons need to know the anatomy and variations of NPC.


Assuntos
Nariz/anatomia & histologia , Palato/anatomia & histologia , Adolescente , Adulto , Idoso , Tomografia Computadorizada de Feixe Cônico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
4.
Folia Morphol (Warsz) ; 78(2): 331-343, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30178457

RESUMO

BACKGROUND: The purpose of this study is to evaluate the anatomy, morphometry, and variations of infraorbital groove (IOG), infraorbital canal (IOC) and infraorbital foramen (IOF) on the cone-beam computed tomography (CBCT) images and to investigate their relations with surrounding structures. METHODS: IOG, IOC and IOF were evaluated retrospectively in CBCT images of 75 female (F) and 75 male (M) cases with a range of 18-65 years (F: 37.62 ± ± 13.55, M: 37.53 ± 15.87) by Planmeca Romexis programme. IOG, IOC and IOF were examined bilaterally (300 sides) in the cases. The 13 parameters were measured on these images in axial, sagittal and coronal planes. RESULTS: There was a very weak positive correlation between the age and the angle between IOC and IOG (p = 0.015, r = 0.198), there was a weak positive correlation between the age and skin thickness (p = 0.001, r = 0.281), and there was no correlation between the age and other parameters. A total of 21 (7%) IOCs were detected in maxillary sinus, bilaterally in 6 cases and unilaterally in 9 cases (5 on the left, 4 on the right). In 1 case, bilaterally, IOC was separated 2 canals while running anteriorly in the maxillary sinus. The larger one was directed to IOF in its normal course and the smaller one was directed to lateral wall of nasal cavity and opened to the inferior nasal meatus in front of the opening of nasolacrimal duct. CONCLUSIONS: We suggest that the parameters found in the present study may facilitate prediction of the location of the infraorbital nerve. Knowledge of this exact position in relation to easily measurable parameters may decrease the risk of infraorbital nerve injury during surgical approaches directed to this region and might serve as a guide during local anaesthetic interventions for dentistry, ophthalmology, plastic surgery, rhinology, neurosurgery and dermatology.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Órbita/diagnóstico por imagem , Órbita/cirurgia , Adolescente , Adulto , Feminino , Humanos , Masculino , Seio Maxilar/diagnóstico por imagem , Pessoa de Meia-Idade , Adulto Jovem
5.
J Neurosci Methods ; 299: 45-54, 2018 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-29471065

RESUMO

BACKGROUND: Clustering approaches used in functional magnetic resonance imaging (fMRI) research use brain activity to divide the brain into various parcels with some degree of homogeneous characteristics, but choosing the appropriate clustering algorithms remains a problem. NEW METHOD: A novel application of the robust unsupervised learning approach is proposed in the current study. Robust growing neural gas (RGNG) algorithm was fed into fMRI data and compared with growing neural gas (GNG) algorithm, which has not been used for this purpose or any other medical application. Learning algorithms proposed in the current study are fed with real and free auditory fMRI datasets. RESULTS: The fMRI result obtained by running RGNG was within the expected outcome and is similar to those found with the hypothesis method in detecting active areas within the expected auditory cortices. COMPARISON WITH EXISTING METHOD(S): The fMRI application of the presented RGNG approach is clearly superior to other approaches in terms of its insensitivity to different initializations and the presence of outliers, as well as its ability to determine the actual number of clusters successfully, as indicated by its performance measured by minimum description length (MDL) and receiver operating characteristic (ROC) analysis. CONCLUSIONS: The RGNG can detect the active zones in the brain, analyze brain function, and determine the optimal number of underlying clusters in fMRI datasets. This algorithm can define the positions of the center of an output cluster corresponding to the minimal MDL value.


Assuntos
Algoritmos , Mapeamento Encefálico/métodos , Encéfalo/fisiologia , Mineração de Dados/métodos , Imageamento por Ressonância Magnética , Aprendizado de Máquina não Supervisionado , Análise por Conglomerados , Humanos , Processamento de Imagem Assistida por Computador , Redes Neurais de Computação , Neurociências/métodos , Processamento de Sinais Assistido por Computador
6.
Folia Morphol (Warsz) ; 77(3): 514-520, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29345723

RESUMO

BACKGROUND: The purpose of this study is to evaluate the anatomical features of lingual foramina and their bony canals in Anatolian ancient mandibles (9-10th century) by using cone beam computed tomography (CBCT). MATERIALS AND METHODS: Fifty-eight ancient dry mandibles were scanned with CBCT. Lingual foramina were grouped into midline, paramedian, posterior foramina and combination of these groups. Midline group was also classified according to internal surface of the mandible (gonial tubercles [GTs]). The incidence, vertical distance and diameter of lingual foramina were measured according to age groups and gender. RESULTS: The incidence of the lingual foramen was 96.6%. Midline of the symphysis had the highest incidence (34.4%) of foramina (p < 0.05), followed by both midline and paramedian type (32.8%; p < 0.05). Classification in terms of GT represented class 3 as the most encountered group (28.6%). Number of foramina observed in the mandibles ranged from 0 to 6 with the incidence of 3.4% and 32.8%, respectively. The male and < 35 years groups presented larger measurement values in midline region (p < 0.05). CONCLUSIONS: Mandibular lingual foramina and bony canals are frequently present in ancient mandibles. When compared with modern subjects, similar findings are observed according to published literatures. CBCT is also proved to be an effective imaging modality in the detection of lingual foramina and canals in anthropological studies.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Mandíbula/diagnóstico por imagem , Feminino , História Medieval , Humanos , Masculino
7.
Pain Pract ; 16(7): 850-5, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-26179674

RESUMO

OBJECTIVES: The aim of this study was to adapt the "Neuropathic Pain Impact on Quality-of-Life Questionnaire" (NePIQoL) into Turkish and to test its validity and reliability in neuropathic pain patients. METHODS: We enrolled 200 chronic pain patients who admitted to the Neurology Department of Kirikkale University, Faculty of Medicine, in our study. Patients were diagnosed with neuropathic or nociceptive pain based on medical history, physical examination, electromyography and nerve conduction studies, laboratory examinations, and imaging techniques. Discriminant analysis was used to diagnose the neuropathic pain regarding sensitivity and specificity. The original version of the NePIQoL was translated into Turkish by standard procedures. RESULTS: Total NePIQoL scores were statistically different between neuropathic and nociceptive pain patients in both the first and second NePIQoL applications (P < 0.001). Cronbach's alpha coefficient of total 12 items of the first and second applications was 0.95. These results suggest a high validity level for the Turkish version of the NePIQoL. CONCLUSIONS: The Turkish version of NePIQoL appears to be reliable and valid for neuropathic pain impact on quality of life in patients with neuropathic pain.


Assuntos
Neuralgia/diagnóstico , Qualidade de Vida , Inquéritos e Questionários , Traduções , Adulto , Dor Crônica/diagnóstico , Feminino , Humanos , Idioma , Masculino , Pessoa de Meia-Idade , Exame Físico , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Turquia
8.
J Pediatr Surg ; 50(4): 540-2, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25840059

RESUMO

BACKGROUND/AIM: Children with attention-deficit/hyperactivity disorder (AD/HD) have risk taking behavior and are more prone to sustaining injury. It is aimed to evaluate the cognitive and behavioral characteristics of children with caustic ingestion. PATIENTS AND METHODS: Ninety two children with a history of nonsuicidal caustic ingestion (CI, n=46) and healthy subjects (HS, n=46) admitted to pediatric surgery department were enrolled into the study. Patients in groups were evaluated for age, sex, number of siblings and educational status of the parents. Before filling the questionnaires, the children were undergone flexible endoscopy and treated accordingly. Conners Parents Rating Scale-revised long form (CPRS-R:L), validated for Turkish Children, was used to evaluate the cognitive and behavioral characteristics of children. Parents rate their child's behavior with a four-point Likert scale. Subscales of CPRS-R:L including cognitive problems/inattention (CG/I), hyperactivity (H), attention deficit hyperactivity disorder index (AD/HD-I), Conners' Global Index-discomfort-impulsivity (CGI-DI), DSM-IV-symptom subscale-inattention (DSMIV, SS-I), DSM-IV-symptom subscale-hyperactivity-impulsivity (DSM-IV, SS-HI), DSMIV-symptom subscale-total score (DSM-IV SS-T) were used to determine the severity of the AD/HD symptom. Demographic features and cognitive/behavioral characteristics of children with caustic ingestion were compared with healthy subjects. RESULTS: The median age of the patients was 4 (2-14 years) in both CI and HS groups. Female male ratio was 13:33 in CI and 12:34 in HS. Sixty seven percent of patients were preschool children (younger than 5 years of age) in both CI and HS groups. There was no difference between groups for number of siblings (p>0.05). Parents of HS group had higher educational status than parents in CI (p<0.05). When subscale scores of CPRS-R:L compared between CI and HS groups, CI group had higher CGI-DI scores than HS (p<0.05). Children younger than five years of age had higher scores of H, emotional instability and total CG/I in CI than HS group (p<0.05). CONCLUSION: Children with caustic ingestion had impulsiveness behavior when compared to healthy children. In addition to impulsivity, hyperactivity can be also assessed as a risk factor for caustic ingestion in children younger than 5years of age. We suggest that association between AD/HD behavior and risk of sustaining injuries was also confirmed for caustic ingestion in children.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/complicações , Queimaduras Químicas/psicologia , Cáusticos/intoxicação , Comportamento Infantil , Cognição , Esôfago/lesões , Adolescente , Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Queimaduras Químicas/etiologia , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Inquéritos e Questionários
9.
Anaesth Intensive Care ; 39(4): 630-4, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21823381

RESUMO

The study objective of this prospective, double-blind randomised controlled study was to evaluate the efficacy of ultrasound guided transversus abdominis plane (TAP) block and bupivacaine infiltration of the skin and subcutaneous tissue of the wound in patients undergoing hysterectomy. Patients were randomly allocated to three groups: a control group (n = 18) and TAP block group (n = 18) received bilateral TAP blocks with saline and bupivacaine respectively, and an infiltration group (n = 19) received skin and subcutaneous wound tissue infiltration with bupivacaine at the end of surgery. After surgery patients received patient-controlled intravenous tramadol and were assessed for pain and tramadol consumption at 1, 2, 4, 6 and 24 hours. Both the TAP and infiltration groups had lower movement and rest pain scores than the control group, with lower scores in the TAP group than the infiltration group at 6 and 24 hours. Total tramadol consumption was significantly lower in the TAP group than in the other groups at all time points. We concluded that ultrasound-guided TAP block reduced rest and movement pain after total abdominal hysterectomy and was more effective than superficial wound infiltration for postoperative pain management.


Assuntos
Abdome/diagnóstico por imagem , Histerectomia/métodos , Bloqueio Nervoso/métodos , Adulto , Idoso , Analgesia Controlada pelo Paciente , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/uso terapêutico , Anestesia Local , Anestésicos Locais/administração & dosagem , Anestésicos Locais/uso terapêutico , Bupivacaína/administração & dosagem , Bupivacaína/uso terapêutico , Método Duplo-Cego , Eletrocardiografia , Determinação de Ponto Final , Feminino , Humanos , Pessoa de Meia-Idade , Medição da Dor , Dor Pós-Operatória/tratamento farmacológico , Estudos Prospectivos , Tramadol/administração & dosagem , Tramadol/uso terapêutico , Ultrassonografia
10.
Folia Morphol (Warsz) ; 70(2): 116-20, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21630233

RESUMO

The biceps brachii (BB) is as one of the most variable muscles in the human body in terms of number and morphology of its heads. The most frequent variation is the presence of a third head, which has been reported by several authors in different populations. Our aim was to find the occurrence of the supernumerary head of BB in Turkish foetuses. Out of the 24 upper limbs of the foetuses, two (8.33%) arms were found to have a three-headed BB. The variations were present unilaterally in the right arm of one male foetus and one female foetus. In one of the cases, the third head of BB originated from the anteromedial aspect of the humerus just distal to the insertion of the coracobrachilais, medial to the brachialis, and in the other the third head was a thin muscle bundle, which arose on the lateral side of the insertion of coracobrachialis and over the origin of the brachialis. Both of them were extended distally and joined the common tendon. The occasional presence of the three-headed BB in the foetuses observed in the present study was similar to those of adults reported in previous studies. In conclusion, these variations are not rare and are interesting not only to anatomists but also to orthopaedic surgeons, plastic surgeons, traumatologists, physiotherapists, doctors dealing with sports medicine, and radiologists.


Assuntos
Braço/anormalidades , Feto/anormalidades , Músculo Esquelético/anormalidades , Anormalidades Musculoesqueléticas/embriologia , Braço/fisiologia , Feminino , Feto/fisiologia , Humanos , Úmero/anormalidades , Úmero/fisiologia , Masculino , Músculo Esquelético/inervação , Músculo Esquelético/fisiologia , Anormalidades Musculoesqueléticas/epidemiologia , Anormalidades Musculoesqueléticas/etnologia , Gravidez , Prevalência , Tendões/anormalidades , Tendões/fisiologia , Turquia/etnologia , População Branca
11.
Acta Anaesthesiol Belg ; 60(3): 185-8, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19961117

RESUMO

Burn scars in early childhood often impairs normal development of the structures of the face. Multiple reconstructive interventions contribute to airway deformity with excessive scar and contracture band formation. Such patients are the most difficult group because of the risk of difficult ventilation and intubation in anesthesiology practice. Although developments in complex airway management techniques are increased, solutions may be achieved with simple approaches. For this purpose, we report about a patient with an anticipated difficult airway who has rejected awake fiberoptic intubation. The patient was managed successfully using classical laryngeal mask airway and nasogastric tube with the guidance of fiberoptic bronchoscope under deep sedation.


Assuntos
Cicatriz/complicações , Intubação Gastrointestinal , Intubação Intratraqueal/métodos , Máscaras Laríngeas , Adolescente , Broncoscopia , Queimaduras/patologia , Cicatriz/patologia , Sedação Profunda , Humanos , Lábio/cirurgia , Masculino , Fibras Ópticas , Procedimentos de Cirurgia Plástica
12.
Eur J Ophthalmol ; 18(5): 675-9, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18850541

RESUMO

PURPOSE: To evaluate serum allergen specific immunoglobulin E (IgE) levels in patients with various types of allergic conjunctivitis. METHODS: Twenty-five patients with seasonal allergic conjunctivitis (SAC), 17 patients with perennial allergic conjunctivitis (PAC), and 10 patients with vernal conjunctivitis (VC) were included in the study. Specific IgE levels to Dermatophagoides pteronyssinus (Dp), Dermatophagoides farinae (Df), mixed grass pollens, and animal epithelia were measured using Pharmacia CAP system (Pharmacia Diagnostic AB, Uppsala, Sweden). RESULTS: The percentage of subjects with specific IgE against Dp and Df was statistically higher in VC (30%) compared to PAC (5.9%) and SAC (0%) (p=0.03). Specific IgE against mixed grass pollens was found in 30% of VC and 40% of SAC, whereas 10% of VC and 8% of SAC patients were found to be hypersensitive to animal epithelia. CONCLUSIONS: Allergic reaction against house dust mites and pollens was common in VC, whereas specific IgE against grass pollens was remarkable in SAC. IgE levels specific to various antigens might be measured by UNICAP system, which is a rapid and practical technology.


Assuntos
Alérgenos/imunologia , Antígenos de Dermatophagoides/imunologia , Antígenos de Plantas/imunologia , Conjuntivite Alérgica/imunologia , Células Epiteliais/imunologia , Imunoglobulina E/sangue , Adolescente , Adulto , Feminino , Humanos , Técnicas Imunoenzimáticas , Masculino , Poaceae/imunologia , Pólen/imunologia , Sensibilidade e Especificidade
13.
Eur J Ophthalmol ; 18(4): 551-5, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18609473

RESUMO

PURPOSE: To study the frequency of exfoliation syndrome (XFS) and its association with intraocular pressure (IOP) and systemic diseases in patients with age-related cataract scheduled for surgery. METHODS: All 1480 cataract patients had a comprehensive systemic and eye examination, including slit-lamp biomicroscopy before and after mydriasis, IOP measurement, gonioscopy, and fundus examination. RESULTS: The percentage of XFS among patients scheduled for cataract surgery was 16.4, with no gender difference (p=0.833). The mean age of XFS patients (74.3+/-7.0 years) was significantly higher when compared to the ones without XFS (66.5+/-10.9 years) (p<0.001). XFS was unilateral in 41.3% of the subjects and bilateral in 58.7%. The number of subjects with XFS increased significantly with aging (p<0.001) (OR=1.093, 95% CI=1.073-1.14) (p<0.001). The most common type of cataract was nuclear in the XFS group (33.5%) and 24.6% of patients with mature cataract had XFS. In the XFS group, 11.2% of the subjects had glaucoma, which was statistically higher than the non-XFS group (4.6%) (p<0.001) (OR=2.67, 95% CI=1.65-4.32). Eighty-four patients had glaucoma and 27 of them (32.1%) had exfoliative glaucoma. The only systemic disease that was found to be associated with XFS was coronary heart disease with an OR of 1.49 (95% CI=1.068-2.072) (p=0.019). CONCLUSIONS: XFS is a common problem in the aging cataract population of Turkey and increased IOP, glaucomatous optic neuropathy, and coronary heart disease occur more frequently in patients with XFS compared with subjects without XFS.


Assuntos
Extração de Catarata , Catarata/epidemiologia , Doença das Coronárias/epidemiologia , Síndrome de Exfoliação/epidemiologia , Glaucoma/epidemiologia , Doenças do Nervo Óptico/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Envelhecimento , Diabetes Mellitus/epidemiologia , Feminino , Humanos , Hipertensão/epidemiologia , Pressão Intraocular , Masculino , Pessoa de Meia-Idade , Prevalência , Doença Pulmonar Obstrutiva Crônica/epidemiologia , Doenças da Glândula Tireoide/epidemiologia , Turquia/epidemiologia , Acuidade Visual
14.
Clin Anat ; 21(2): 119-26, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18189278

RESUMO

The conventional approach to the fourth ventricle is by splitting the vermis on the suboccipital surface of the cerebellum. By a unilateral transcerebellomedullary fissure approach, it is possible to provide sufficient operative space from cerebral aqueduct to obex without splitting the vermis. This approach needs meticulous dissection of the cerebellomedullary fissure and preservation of the posterior inferior cerebellar artery (PICA) and its branches. The tonsillomedullary and telovelotonsillar segments of the PICA are the most important vessels encountered in the transcerebellomedullary fissure approach. The PICA was examined under a surgical microscope in a total of 40 specimens by perfusing with a mixture of 10% Indian ink and gelatin. The passing of the tonsillomedullary segment of the PICA through the cerebellomedullary fissure was observed superior to the tonsil in 5%, at the level of the upper pole of the tonsil in 17.5%, at the middle of the tonsil in 37.5% and at the level of the lower pole of the tonsil in 37.5% specimens. When the PICA arose from the lateral medullary (LM) segment of the vertebral artery (VA), a caudal loop was present in 90%, when the PICA originated from the premedullary segment of the VA, the loop was present in 87.5% specimens. When the PICA arose from the basilar artery (BA), the loop was absent, and the tonsillomedullary segment of the PICA showed a straight course (100%). A thorough understanding of the relationship of the branches of the PICA to the cerebellar tonsils are prerequisites for surgery in and around the fourth ventricle.


Assuntos
Artéria Basilar/anatomia & histologia , Cerebelo/irrigação sanguínea , Quarto Ventrículo/anatomia & histologia , Bulbo/anatomia & histologia , Procedimentos Neurocirúrgicos/métodos , Humanos , Perfusão
15.
Clin Anat ; 20(8): 886-91, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17907205

RESUMO

The posterior inferior cerebellar artery (PICA) is the largest branch of the vertebral artery. It usually arises at the anterolateral margin of the medulla oblongata close to the lower cranial nerves. The PICA had the most complex relationship to the cranial nerves of any artery and it is frequently exposed in approaches directed to the fourth ventricle. The aim of this article is to describe the anatomical relationship of the PICA to the lower cranial nerves. In this study, 12.5% of PICAs passed between the glossopharyngeal and vagus nerves, 20% between the vagus and accessory nerves, and 65% through the rootlets of the accessory nerve. The lateral medullary segment of the PICA showed a lateral loop which in 20% specimens pressed against the inferior surfaces of the facial and vestibulocochlear nerves. The lateral medullary segment of the PICA in 20% specimens passed superior to the hypoglossal nerve, in 47.5% through the rootlets of the hypoglossal nerve, and in 30% inferior to the hypoglossal nerve. The findings on the relationship of the PICA to the lower cranial nerves could be helpful in microsurgery of this region.


Assuntos
Nervo Facial/anatomia & histologia , Nervo Hipoglosso/anatomia & histologia , Artéria Vertebral/anatomia & histologia , Nervo Glossofaríngeo/anatomia & histologia , Humanos , Nervo Vago/anatomia & histologia , Nervo Vestibulococlear/anatomia & histologia
16.
Eur J Ophthalmol ; 16(5): 667-73, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17061216

RESUMO

PURPOSE: To evaluate the results of short wavelength perimetry (SWAP) of ocular hypertensive (OHT) patients and correlate these findings with central corneal thickness (CCT) measurements. METHODS: Thirty-seven OHT patients with a mean age of 50.2+/-8.2 (SD) years and 30 control subjects with a mean age of 50.3+/-8.5 (SD) years were included in this study. A questionnaire was applied to patients to evaluate the demographic risk factors that may predict glaucoma development. After a detailed ophthalmologic examination, achromatic and short wavelength perimetries and ultrasonic pachymetry were performed and the results were compared between the two groups with Student t test and Mann-Whitney U test. A p value<0.05 is considered as statistically significant. RESULTS: Mean CCT was higher in the OHT group (right eye; 558.13+/-28.39 microm and left eye; 558.94+/-27.30 microm) when compared with the control subjects (524.66+/-30.53 microm and 525.86+/-30.46 microm, respectively) (p<0.01). A significant positive correlation was found between CCT measurements and intraocular pressure (r=0.5, p<0.001). Four right eyes (10.8%) and five left eyes (13.5%) of OHT patients had defects in SWAP. OHT patients with SWAP abnormalities had significantly lower CCT measurements in right (527.25+/-17.34 microm) and left eye (528.80+/-13.60 microm) when compared with OHT patients without SWAP defects (561.87+/-27.29 microm and 563.65+/-25.92 microm, respectively) (p<0.05). Significant correlations were found between CCT and SWAP MD, PSD, and CPSD (p<0.05). CONCLUSIONS: OHT patients with SWAP abnormalities had significantly lower CCT measurements than those without. CCT is considered as a risk factor for the development of glaucomatous damage in OHT patients.


Assuntos
Córnea/diagnóstico por imagem , Hipertensão Ocular/fisiopatologia , Testes de Campo Visual/métodos , Campos Visuais/fisiologia , Feminino , Seguimentos , Humanos , Pressão Intraocular , Masculino , Pessoa de Meia-Idade , Hipertensão Ocular/diagnóstico por imagem , Prognóstico , Estudos Retrospectivos , Índice de Gravidade de Doença , Ultrassonografia
18.
Pain Pract ; 5(3): 251-4, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17147588

RESUMO

Caudal epidural steroid injections are often used for low back pain. Fluoroscopic guidance has been frequently cited as a requirement for this procedure. In this preliminary report, we demonstrate that fluoroscopic guidance for caudal epidural Tuohy needle placement without real-time imaging may result in inadvertent intravenous injection of the drug. We detected intravenous leakage of the drug in 4 cases of 10 when real-time fluoroscopic imaging was used. Thus, real-time imaging may be recommended in addition to routine fluoroscopic guidance for caudal epidural procedures, as it may improve efficacy and safety by assuring accurate drug deposition.

19.
Eur J Ophthalmol ; 13(4): 377-82, 2003 May.
Artigo em Inglês | MEDLINE | ID: mdl-12872795

RESUMO

PURPOSE: To measure the retinal nerve fiber layer thickness in patients with pigment dispersion syndrome (PDS) using scanning laser polarimetry and to compare these measurements with those of normal subjects and patients with pigmentary glaucoma (PG). METHODS: Age-, sex-, and refractive error-matched subjects--18 patients with PDS, 18 patients with PG, and 20 healthy subjects--were evaluated by scanning laser polarimetry (Nerve Fiber Analyzer [NFA] GDx). The NFA did not have a compensator for corneal polarization. One randomly selected eye from each patient was included in the statistical analysis. The NFA measurements of patients with PDS and PG and healthy subjects were compared statistically using analysis of variance, Tukey multiple comparisons, chi-square, and independent t-tests. RESULTS: The mean values for average thickness, superior and inferior maximum, superior and inferior average, ellipse average thickness, and superior integral were found to be lower in the patients with PDS (p < 0.02) and PG (p < 0.005) compared to the normal subjects. The mean values for maximum modulation, superior ratio, inferior ratio, and superior/nasal ratio in PDS were in between those of the PG and control groups (p > 0.05). The ellipse modulation was significantly lower in the PG group when compared to the other two groups (p < 0.03). CONCLUSIONS: Retinal nerve fiber loss is present to some extent in patients with PDS and this loss is not age or sex dependent. Parameters of modulation might be more representative of significant damage of the nerve fiber layer.


Assuntos
Oftalmopatias/patologia , Glaucoma de Ângulo Aberto/patologia , Lasers , Fibras Nervosas/patologia , Transtornos da Pigmentação/patologia , Retina/patologia , Adulto , Idoso , Birrefringência , Estudos de Casos e Controles , Técnicas de Diagnóstico Oftalmológico , Feminino , Humanos , Masculino , Microscopia de Polarização , Pessoa de Meia-Idade
20.
Eur J Ophthalmol ; 13(2): 202-6, 2003 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-12696641

RESUMO

PURPOSE: Either autogenous or allograft fascia lata frontal sling procedures can be used for the treatment of severe ptosis. We retrospectively evaluated the late outcomes of both approaches. METHODS: Medical records of patients who underwent frontal sling ptosis surgery between 1978 and 2000, with a follow-up of one year or more were included in the study. Success rates and the complications of the surgery for autogenous and allograft fascia lata were recorded. The results were compared statistically. RESULTS: Surgeries were performed with 82 autogenous or 43 allograft fascia lata. At last follow-up there were 71 eyes (86.6%) with good, 8 eyes (9.7%) with moderate, 3 eyes (3.7%) with poor results after autogenous fascia lata and 35 (81.4%), 3 (7%) and 5 (11.6%) after the allograft fascia lata frontal sling procedure. There was no significant difference between the two groups. Repeat surgery was carried out on three patients after autogenous and five after allograft fascia lata surgery. Two cases of preseptal cellulitis were observed, one abscess after autogenous and one lagophthalmus after allograft fascia lata sling surgery. All patients had slight edema early after surgery which resolved in a few days. Only one patient developed a hematoma at the site of the leg incision. CONCLUSIONS: Although the long-term success rate with the autogenous fascia lata is slightly higher and this remains the first choice, allograft fascia lata is a good alternative in patients in whom fascia could not be harvested.


Assuntos
Blefaroplastia/métodos , Blefaroptose/cirurgia , Fascia Lata/transplante , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Humanos , Complicações Intraoperatórias , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Reoperação , Estudos Retrospectivos , Transplante Autólogo , Transplante Homólogo , Resultado do Tratamento
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...